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A Diffusion-like Process Accommodates New Crypts During Clonal Expansion in Human Colonic Epithelium.
Olpe, Cora; Khamis, Doran; Chukanova, Maria; Skoufou-Papoutsaki, Nefeli; Kemp, Richard; Marks, Kate; Tatton, Cerys; Lindskog, Cecilia; Nicholson, Anna; Brunton-Sim, Roxanne; Malhotra, Shalini; Ten Hoopen, Rogier; Stanley, Rachael; Winton, Douglas J; Morrissey, Edward.
Afiliação
  • Olpe C; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom; Wellcome Trust-Medical Research Council, Cambridge Stem Cell Institute, Cambridge, UK.
  • Khamis D; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, United Kingdom.
  • Chukanova M; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom.
  • Skoufou-Papoutsaki N; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom; Wellcome Trust-Medical Research Council, Cambridge Stem Cell Institute, Cambridge, UK.
  • Kemp R; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom.
  • Marks K; Pathology and Data Analytics, St James's University Hospital, Leeds, United Kingdom.
  • Tatton C; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom.
  • Lindskog C; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Nicholson A; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom.
  • Brunton-Sim R; Norwich Research Park BioRepository, Norwich, United Kingdom.
  • Malhotra S; Department of Oncology, University of Cambridge, Cambridge, United Kingdom.
  • Ten Hoopen R; Department of Oncology, University of Cambridge, Cambridge, United Kingdom.
  • Stanley R; Norwich Research Park BioRepository, Norwich, United Kingdom.
  • Winton DJ; Cancer Research-UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, United Kingdom; Wellcome Trust-Medical Research Council, Cambridge Stem Cell Institute, Cambridge, UK. Electronic address: doug.winton@cruk.cam.ac.uk.
  • Morrissey E; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, United Kingdom. Electronic address: edward.morrissey@imm.ox.ac.uk.
Gastroenterology ; 161(2): 548-559.e23, 2021 08.
Article em En | MEDLINE | ID: mdl-33895166
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Colorretais / Transformação Celular Neoplásica / Pólipos do Colo / Proteínas Proto-Oncogênicas p21(ras) / Proliferação de Células / Células Epiteliais / Histona Desmetilases / Mucosa Intestinal / Mutação Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Gastroenterology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Colorretais / Transformação Celular Neoplásica / Pólipos do Colo / Proteínas Proto-Oncogênicas p21(ras) / Proliferação de Células / Células Epiteliais / Histona Desmetilases / Mucosa Intestinal / Mutação Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Gastroenterology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido