pH Dependence of T2 for Hyperpolarizable 13C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging.

Grashei, Martin; Hundshammer, Christian; van Heijster, Frits H A; Topping, Geoffrey J; Schilling, Franz

pH Dependence of T₂ for Hyperpolarizable ¹³C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging.

Grashei, Martin; Hundshammer, Christian; van Heijster, Frits H A; Topping, Geoffrey J; Schilling, Franz.

Afiliação

Grashei M; Department of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar, Technical University of Munich, D-81675 Munich, Germany.
Hundshammer C; Department of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar, Technical University of Munich, D-81675 Munich, Germany.
van Heijster FHA; Department of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar, Technical University of Munich, D-81675 Munich, Germany.
Topping GJ; Department of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar, Technical University of Munich, D-81675 Munich, Germany.
Schilling F; Department of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar, Technical University of Munich, D-81675 Munich, Germany.

Pharmaceuticals (Basel) ; 14(4)2021 Apr 02.

Article em En | MEDLINE | ID: mdl-33918366

Palavras-chave

13C-labeled biomolecules; T2 relaxation time constant; [1-13C]acetate; [1-13C]pyruvate; hyperpolarization; hyperpolarized MRI; magnetic resonance spectroscopy; pH

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha