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Development of Selective FXIa Inhibitors Based on Cyclic Peptides and Their Application for Safe Anticoagulation.
Carle, Vanessa; Wu, Yuteng; Mukherjee, Rakesh; Kong, Xu-Dong; Rogg, Chloé; Laurent, Quentin; Cecere, Enza; Villequey, Camille; Konakalla, Madhuree S; Maric, Tamara; Lamers, Christina; Díaz-Perlas, Cristina; Butler, Kaycie; Goto, Junko; Stegmayr, Bernd; Heinis, Christian.
Afiliação
  • Carle V; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Wu Y; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Mukherjee R; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Kong XD; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Rogg C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Laurent Q; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Cecere E; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Villequey C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Konakalla MS; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Maric T; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Lamers C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Díaz-Perlas C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Butler K; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Goto J; Department of Public Health and Clinical Medicine, University of Umeå, SE-901 87 Umeå, Sweden.
  • Stegmayr B; Department of Public Health and Clinical Medicine, University of Umeå, SE-901 87 Umeå, Sweden.
  • Heinis C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
J Med Chem ; 64(10): 6802-6813, 2021 05 27.
Article em En | MEDLINE | ID: mdl-33974422
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Fator XIa / Anticoagulantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Fator XIa / Anticoagulantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça