Inhibition of cell-intrinsic NF-&#954;B activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus.

Abdellatef, Amira A; Fathy, Moustafa; Mohammed, Abd El-Salam I; Bakr, Marwa S Abu; Ahmed, Amal H; Abbass, Hatem S; El-Desoky, Ahmed H; Morita, Hiroyuki; Nikaido, Toshio; Hayakawa, Yoshihiro

Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus.

Abdellatef, Amira A; Fathy, Moustafa; Mohammed, Abd El-Salam I; Bakr, Marwa S Abu; Ahmed, Amal H; Abbass, Hatem S; El-Desoky, Ahmed H; Morita, Hiroyuki; Nikaido, Toshio; Hayakawa, Yoshihiro.

Afiliação

Abdellatef AA; Institute of Natural Medicine, University of Toyama, Sugitani 2630, Toyama, 930-0194, Japan.
Fathy M; Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Mohammed AEI; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.
Bakr MSA; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Ahmed AH; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Abbass HS; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
El-Desoky AH; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Morita H; Institute of Natural Medicine, University of Toyama, Sugitani 2630, Toyama, 930-0194, Japan.
Nikaido T; Pharmaceutical Industries Research Division, Pharmacognosy Department, National Research Centre, Giza, Egypt.
Hayakawa Y; Institute of Natural Medicine, University of Toyama, Sugitani 2630, Toyama, 930-0194, Japan.

J Nat Med ; 75(4): 840-853, 2021 Sep.

Article em En | MEDLINE | ID: mdl-33988779

Assuntos

Aloe; Neoplasias da Mama; Emodina; Antraquinonas/farmacologia; Neoplasias da Mama/tratamento farmacológico; Emodina/farmacologia; Feminino; Humanos; NF-kappa B

Palavras-chave

Aloe-emodin; Anti-cancer; Asphodelus microcarpus; Breast cancer; Metastasis; NF-κB

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Mama / Emodina / Aloe Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: J Nat Med Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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