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Safety, tolerability, and immune-biomarker profiling for year-long sargramostim treatment of Parkinson's disease.
Olson, Katherine E; Namminga, Krista L; Lu, Yaman; Schwab, Aaron D; Thurston, Mackenzie J; Abdelmoaty, Mai M; Kumar, Vikas; Wojtkiewicz, Melinda; Obaro, Helen; Santamaria, Pamela; Mosley, R Lee; Gendelman, Howard E.
Afiliação
  • Olson KE; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Namminga KL; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Lu Y; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Schwab AD; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Thurston MJ; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Abdelmoaty MM; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, NE 68198, USA.
  • Kumar V; Department of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, NE 68198, USA.
  • Wojtkiewicz M; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Obaro H; Great Plains Center for Clinical and Translational Research, University of Nebraska, USA.
  • Santamaria P; Neurology Consultants of Nebraska, PC and Nebraska Medicine, Medical Center, Omaha, NE, USA.
  • Mosley RL; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA.
  • Gendelman HE; Department of Pharmacology and Experimental Neuroscience, Center for Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha , NE 68198, USA. Electronic address: hegendel@unmc.edu.
EBioMedicine ; 67: 103380, 2021 May.
Article em En | MEDLINE | ID: mdl-34000620

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença de Parkinson / Fator Estimulador de Colônias de Granulócitos e Macrófagos / Antiparkinsonianos Limite: Aged / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença de Parkinson / Fator Estimulador de Colônias de Granulócitos e Macrófagos / Antiparkinsonianos Limite: Aged / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos