[Postoperative Relapse of Combined LargeâCell Neuroendocrine Carcinoma of the Lung with a Remarkable Transient Response to Amrubicin Monotherapy in an Elderly Patient-A Case Report].
Gan To Kagaku Ryoho
; 48(5): 681-683, 2021 May.
Article
em Ja
| MEDLINE
| ID: mdl-34006713
ABSTRACT
An 86âyearâold man with chronic kidney disease underwent surgical resection for combined largeâcell neuroendocrine carcinoma of the left lower lobe of the lung(pT2aN1M0, stage â
¡B). Five months later, multiple liver and bone metastases and mediastinal lymph node recurrence were detected. After 9 courses of amrubicin monotherapy(32 mg/m2 for 3 consecutive days), his tumor marker levels normalized, and radiological examination revealed a complete tumor response. Adverse events occurred, but they were tolerable except a decrease in the neutrophil count. The patient remained in good condition for several months but died of tumor relapse 22 months after the initial recurrence. Amrubicin monotherapy was considered to be one of the treatment choices for recurrent largeâcell neuroendocrine carcinoma of the lung in elderly patients.
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Bases de dados:
MEDLINE
Assunto principal:
Carcinoma Neuroendócrino
/
Neoplasias Pulmonares
Limite:
Aged
/
Aged80
/
Humans
/
Male
Idioma:
Ja
Revista:
Gan To Kagaku Ryoho
Ano de publicação:
2021
Tipo de documento:
Article