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Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP-HIPK2 axis.
Jin, Xiaofeng; Qing, Shi; Li, Qian; Zhuang, Hui; Shen, Liliang; Li, Jinhui; Qi, Honggang; Lin, Ting; Lin, Zihan; Wang, Jian; Cao, Xinyi; Yang, Jianye; Ma, Qi; Cong, Linghua; Xi, Yang; Fang, Shuai; Meng, Xiaodan; Gong, Zhaohui; Ye, Meng; Wang, Shuyun; Wang, Chenji; Gao, Kun.
Afiliação
  • Jin X; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Qing S; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Li Q; State Key Lab of Genetic Engineering, MOE Engineering Research Center of Gene Technology, School of Life Sciences, Fudan University, Shanghai 200438, China.
  • Zhuang H; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Shen L; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Li J; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Qi H; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Lin T; Department of Urology, Department of Hematology, the Affiliated Yinzhou Renmin Hospital of Medical School of Ningbo University, Ningbo 315040, China.
  • Lin Z; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Wang J; Department of Urology, the Affiliated Yinzhou Second Hospital of Medical School of Ningbo University, Ningbo 315100, China.
  • Cao X; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Yang J; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Ma Q; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Cong L; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Xi Y; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Fang S; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Meng X; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Gong Z; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Ye M; The Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
  • Wang S; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Medical School of Ningbo University, Ningbo 315211, China.
  • Wang C; Translational Research Laboratory for Urology, the Key Laboratory of Ningbo City. Ningbo First Hospital, The affiliated hospital of Ningbo University, Ningbo, Zhejiang 315010, China.
  • Gao K; Department of Urology, Department of Hematology, the Affiliated Yinzhou Renmin Hospital of Medical School of Ningbo University, Ningbo 315040, China.
Nucleic Acids Res ; 49(12): 6788-6803, 2021 07 09.
Article em En | MEDLINE | ID: mdl-34133717

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas Repressoras / Proteínas Nucleares / Proteínas de Transporte / Proteínas Serina-Treonina Quinases / Instabilidade Genômica Tipo de estudo: Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas Repressoras / Proteínas Nucleares / Proteínas de Transporte / Proteínas Serina-Treonina Quinases / Instabilidade Genômica Tipo de estudo: Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China