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Metabolic modeling of single Th17 cells reveals regulators of autoimmunity.
Wagner, Allon; Wang, Chao; Fessler, Johannes; DeTomaso, David; Avila-Pacheco, Julian; Kaminski, James; Zaghouani, Sarah; Christian, Elena; Thakore, Pratiksha; Schellhaass, Brandon; Akama-Garren, Elliot; Pierce, Kerry; Singh, Vasundhara; Ron-Harel, Noga; Douglas, Vivian Paraskevi; Bod, Lloyd; Schnell, Alexandra; Puleston, Daniel; Sobel, Raymond A; Haigis, Marcia; Pearce, Erika L; Soleimani, Manoocher; Clish, Clary; Regev, Aviv; Kuchroo, Vijay K; Yosef, Nir.
Afiliação
  • Wagner A; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA 94720, USA; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
  • Wang C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada; Department of Immunology
  • Fessler J; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • DeTomaso D; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
  • Avila-Pacheco J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Kaminski J; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
  • Zaghouani S; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Christian E; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Thakore P; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Schellhaass B; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA 94720, USA.
  • Akama-Garren E; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Pierce K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Singh V; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Ron-Harel N; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Biology, Technion, Israel Institute of Technology, Haifa 3200003, Israel.
  • Douglas VP; Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.
  • Bod L; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Schnell A; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Puleston D; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
  • Sobel RA; Palo Alto Veteran's Administration Health Care System and Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Haigis M; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Pearce EL; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
  • Soleimani M; Department of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87121, USA.
  • Clish C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Regev A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02140, USA.
  • Kuchroo VK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address: vkuchroo@evergrande.hms.harvard.edu.
  • Yosef N; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA 94720, USA; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA; Ragon Institute of MGH, MIT, an
Cell ; 184(16): 4168-4185.e21, 2021 08 05.
Article em En | MEDLINE | ID: mdl-34216539

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Autoimunidade / Células Th17 / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Autoimunidade / Células Th17 / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos