Delineating the Ligand-Receptor Interactions That Lead to Biased Signaling at the µ-Opioid Receptor.

Kelly, Brendan; Hollingsworth, Scott A; Blakemore, David C; Owen, Robert M; Storer, R Ian; Swain, Nigel A; Aydin, Deniz; Torella, Rubben; Warmus, Joseph S; Dror, Ron O

Kelly, Brendan; Hollingsworth, Scott A; Blakemore, David C; Owen, Robert M; Storer, R Ian; Swain, Nigel A; Aydin, Deniz; Torella, Rubben; Warmus, Joseph S; Dror, Ron O.

Afiliação

Kelly B; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology & Institute for Computational and Mathematical Engineering, Stanford University, Stanford, California 94305, United States.
Hollingsworth SA; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology & Institute for Computational and Mathematical Engineering, Stanford University, Stanford, California 94305, United States.
Blakemore DC; Pfizer Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Owen RM; Pfizer Medicine Design, The Portway, Granta Park, Cambridge CB21 6GS, U.K.
Storer RI; Pfizer Medicine Design, The Portway, Granta Park, Cambridge CB21 6GS, U.K.
Swain NA; Pfizer Medicine Design, The Portway, Granta Park, Cambridge CB21 6GS, U.K.
Aydin D; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology & Institute for Computational and Mathematical Engineering, Stanford University, Stanford, California 94305, United States.
Torella R; Pfizer Medicine Design, 610 Main Street, Cambridge, Massachusetts 02139, United States.
Warmus JS; Pfizer Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Dror RO; Departments of Computer Science, Molecular and Cellular Physiology, and Structural Biology & Institute for Computational and Mathematical Engineering, Stanford University, Stanford, California 94305, United States.

J Chem Inf Model ; 61(7): 3696-3707, 2021 07 26.

Article em En | MEDLINE | ID: mdl-34251810

Assuntos

Receptores Opioides mu; Transdução de Sinais; Proteínas de Ligação ao GTP; Humanos; Ligantes; Dor; Ligação Proteica; Receptores Opioides mu/metabolismo

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores Opioides mu Limite: Humans Idioma: En Revista: J Chem Inf Model Assunto da revista: INFORMATICA MEDICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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