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Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
Augsberger, Christian; Hänel, Gerulf; Xu, Wei; Pulko, Vesna; Hanisch, Lydia Jasmin; Augustin, Angelique; Challier, John; Hunt, Katharina; Vick, Binje; Rovatti, Pier Eduardo; Krupka, Christina; Rothe, Maurine; Schönle, Anne; Sam, Johannes; Lezan, Emmanuelle; Ducret, Axel; Ortiz-Franyuti, Daniela; Walz, Antje-Christine; Benz, Jörg; Bujotzek, Alexander; Lichtenegger, Felix S; Gassner, Christian; Carpy, Alejandro; Lyamichev, Victor; Patel, Jigar; Konstandin, Nikola; Tunger, Antje; Schmitz, Marc; von Bergwelt-Baildon, Michael; Spiekermann, Karsten; Vago, Luca; Jeremias, Irmela; Marrer-Berger, Estelle; Umaña, Pablo; Klein, Christian; Subklewe, Marion.
Afiliação
  • Augsberger C; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Hänel G; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Xu W; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Pulko V; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Hanisch LJ; Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Augustin A; Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Challier J; Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Hunt K; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Vick B; Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Rovatti PE; Research Unit Apoptosis in Hematopoietic Stem Cells (AHS), Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
  • Krupka C; Research Unit Apoptosis in Hematopoietic Stem Cells (AHS), Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
  • Rothe M; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Schönle A; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Sam J; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Lezan E; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Ducret A; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Ortiz-Franyuti D; Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Walz AC; Roche Pharma Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Benz J; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Bujotzek A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Lichtenegger FS; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Gassner C; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Carpy A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Lyamichev V; Roche Pharma Research & Early Development, Roche Innovation Center Munich, Penzberg, Germany.
  • Patel J; Roche Pharma Research & Early Development, Roche Innovation Center Munich, Penzberg, Germany.
  • Konstandin N; Roche Pharma Research & Early Development, Roche Innovation Center Munich, Penzberg, Germany.
  • Tunger A; Roche Pharma Research & Early Development, Roche Innovation Center Munich, Penzberg, Germany.
  • Schmitz M; Nimble Therapeutics, Madison, WI.
  • von Bergwelt-Baildon M; Nimble Therapeutics, Madison, WI.
  • Spiekermann K; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Vago L; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Jeremias I; National Center for Tumor Diseases, Partner Site Dresden, Dresden, Germany.
  • Marrer-Berger E; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Umaña P; National Center for Tumor Diseases, Partner Site Dresden, Dresden, Germany.
  • Klein C; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Subklewe M; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
Blood ; 138(25): 2655-2669, 2021 12 23.
Article em En | MEDLINE | ID: mdl-34280257
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeos / Leucemia Mieloide Aguda / Anticorpos Biespecíficos / Proteínas WT1 / Antineoplásicos Imunológicos Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Peptídeos / Leucemia Mieloide Aguda / Anticorpos Biespecíficos / Proteínas WT1 / Antineoplásicos Imunológicos Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha