Differences in the number of de novo mutations between individuals are due to small family-specific effects and stochasticity.

Goldmann, Jakob M; Hampstead, Juliet E; Wong, Wendy S W; Wilfert, Amy B; Turner, Tychele N; Jonker, Marianne A; Bernier, Raphael; Huynen, Martijn A; Eichler, Evan E; Veltman, Joris A; Maxwell, George L; Gilissen, Christian

Goldmann, Jakob M; Hampstead, Juliet E; Wong, Wendy S W; Wilfert, Amy B; Turner, Tychele N; Jonker, Marianne A; Bernier, Raphael; Huynen, Martijn A; Eichler, Evan E; Veltman, Joris A; Maxwell, George L; Gilissen, Christian.

Afiliação

Goldmann JM; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Hampstead JE; Department of Human Genetics, Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Wong WSW; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Wilfert AB; Department of Human Genetics, Donders Centre for Neuroscience, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Turner TN; Inova Translational Medicine Institute (ITMI), Inova Health Systems, Falls Church, Virginia 22042, USA.
Jonker MA; Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Bernier R; Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Huynen MA; Department for Health Evidence, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Eichler EE; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, USA.
Veltman JA; Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre, Nijmegen 6525 GA, The Netherlands.
Maxwell GL; Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Gilissen C; Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, USA.

Genome Res ; 31(9): 1513-1518, 2021 09.

Article em En | MEDLINE | ID: mdl-34301630

Assuntos

Células Germinativas; Humanos; Mutação

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células Germinativas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google