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Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer.
Guerra, Emanuela; Trerotola, Marco; Relli, Valeria; Lattanzio, Rossano; Tripaldi, Romina; Vacca, Giovanna; Ceci, Martina; Boujnah, Khouloud; Garbo, Valeria; Moschella, Antonino; Zappacosta, Romina; Simeone, Pasquale; de Lange, Robert; Weidle, Ulrich H; Rotelli, Maria Teresa; Picciariello, Arcangelo; Depalo, Raffaella; Querzoli, Patrizia; Pedriali, Massimo; Bianchini, Enzo; Angelucci, Domenico; Pizzicannella, Giuseppe; Di Loreto, Carla; Piantelli, Mauro; Antolini, Laura; Sun, Xiao-Feng; Altomare, Donato F; Alberti, Saverio.
Afiliação
  • Guerra E; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Trerotola M; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Relli V; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Oncoxx Biotech, 66034 Lanciano (Chieti), Italy.
  • Lattanzio R; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.
  • Tripaldi R; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Vacca G; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Ceci M; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Boujnah K; Unit of Medical Genetics, Department of Biomedical Sciences - BIOMORF, University of Messina, 98125 Messina, Italy.
  • Garbo V; Unit of Medical Genetics, Department of Biomedical Sciences - BIOMORF, University of Messina, 98125 Messina, Italy.
  • Moschella A; Unit of Medical Genetics, Department of Biomedical Sciences - BIOMORF, University of Messina, 98125 Messina, Italy.
  • Zappacosta R; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Simeone P; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • de Lange R; Roche Diagnostics GmbH, Pharma Research, D-82372 Penzberg, Germany.
  • Weidle UH; Roche Diagnostics GmbH, Pharma Research, D-82372 Penzberg, Germany.
  • Rotelli MT; General Surgery and Liver Transplantation Unit, Department of Emergency and Organ Transplantation, University 'Aldo Moro', 70124 Bari, Italy.
  • Picciariello A; General Surgery and Liver Transplantation Unit, Department of Emergency and Organ Transplantation, University 'Aldo Moro', 70124 Bari, Italy.
  • Depalo R; Oncologic Institute IRCCS "Giovanni Paolo II, 70124 Bari, Italy.
  • Querzoli P; Section of Anatomic Pathology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.
  • Pedriali M; Operative Unit of Surgical Pathology, University Hospital, 44124 Ferrara, Italy.
  • Bianchini E; Operative Unit of Surgical Pathology, University Hospital, 44124 Ferrara, Italy.
  • Angelucci D; Department of Pathology, Chieti Hospital, 66100 Chieti, Italy.
  • Pizzicannella G; Department of Pathology, ASL2 Chieti-Lanciano-Vasto, 66100 Chieti, Italy.
  • Di Loreto C; Department of Pathology, University of Udine, 33100 Udine, Italy.
  • Piantelli M; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
  • Antolini L; Department of Clinical Medicine,Center for Biostatistics, Prevention and Biotechnology, University of Milano-Bicocca, 20900 Monza, Italy.
  • Sun XF; Department of Oncology, and Department of Biomedical and Clinical Sciences Linköping University, SE-581 85 Linköping, Sweden.
  • Altomare DF; Roche Diagnostics GmbH, Pharma Research, D-82372 Penzberg, Germany; General Surgery and Liver Transplantation Unit, Department of Emergency and Organ Transplantation, University 'Aldo Moro', 70124 Bari, Italy.
  • Alberti S; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Oncoxx Biotech, 66034 Lanciano (Chieti), Italy; Unit of Medical Genetics, Department of Biomedical Sciences - BIOMORF, University of Messina, 98125 M
Neoplasia ; 23(9): 898-911, 2021 09.
Article em En | MEDLINE | ID: mdl-34320447
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Antígenos CD / Caderinas / Moléculas de Adesão Celular / Neoplasias do Colo / Perfilação da Expressão Gênica / Secretases da Proteína Precursora do Amiloide / Transição Epitelial-Mesenquimal / Proteína ADAM10 / Proteínas de Membrana / Antígenos de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Neoplasia Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Antígenos CD / Caderinas / Moléculas de Adesão Celular / Neoplasias do Colo / Perfilação da Expressão Gênica / Secretases da Proteína Precursora do Amiloide / Transição Epitelial-Mesenquimal / Proteína ADAM10 / Proteínas de Membrana / Antígenos de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Neoplasia Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália