Predicted limited redistribution of T cells to secondary lymphoid tissue correlates with increased risk of haematological malignancies in asplenic patients.

Kmieciak, Aleksandra E; Brown, Liam V; Coles, Mark C; Wagg, Jonathan; Phipps, Alex; Gaffney, Eamonn A

Kmieciak, Aleksandra E; Brown, Liam V; Coles, Mark C; Wagg, Jonathan; Phipps, Alex; Gaffney, Eamonn A.

Afiliação

Kmieciak AE; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Andrew Wiles Building, Woodstock Rd, Oxford, OX2 6GG, UK. kmieciak@maths.ox.ac.uk.
Brown LV; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Andrew Wiles Building, Woodstock Rd, Oxford, OX2 6GG, UK.
Coles MC; Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Dr, Headington, Oxford, OX3 7FY, UK.
Wagg J; AC Immune, EPFL Innovation Park, 1015, Lausanne, Switzerland.
Phipps A; Pharmaceutical Sciences-Clinical Pharmacology Roche Innovation Centre Welwyn 6 Falcon Way, Shire Park, Welwyn Garden City, AL7 1TW, UK.
Gaffney EA; Clinical Pharmacology and Quantitative Pharmacology-Oncoloy, AstraZeneca, Cambridge, CB2 0AA, UK.

Sci Rep ; 11(1): 16394, 2021 08 12.

Article em En | MEDLINE | ID: mdl-34385480

Assuntos

Neoplasias Hematológicas/imunologia; Tecido Linfoide/imunologia; Esplenopatias/imunologia; Linfócitos T/imunologia; Humanos; Linfócitos/imunologia; Baço/imunologia; Esplenectomia/métodos

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Esplenopatias / Linfócitos T / Neoplasias Hematológicas / Tecido Linfoide Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

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