Behavioral Inflexibility Across Two Neurogenetic Conditions: Down Syndrome and Fragile X Syndrome.
Am J Intellect Dev Disabil
; 126(5): 409-420, 2021 09 01.
Article
em En
| MEDLINE
| ID: mdl-34428269
ABSTRACT
Behavioral inflexibility (BI) has been highlighted to occur across genetic and neurodevelopmental disorders. This study characterized BI in two common neurogenetic conditions Fragile X syndrome (FXS) and Down syndrome (DS). Caregivers of children with FXS (N = 56; with ASD = 28; FXS only = 28) and DS (N = 146) completed the Behavioral Inflexibility Scale (BIS) via an online survey. Total BIS scores were higher in FXS+ASD than both FXS only and DS (p <.001). Most endorsed items were similar across the three groups, but scores were higher in the FXS+ASD group. In all groups, BI associated with other clinical variables (receptive behaviors, anxiety, social communication). The current data suggest that BI is variable across neurogenetic conditions and higher in individuals with comorbid ASD.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Síndrome de Down
/
Transtorno do Espectro Autista
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Síndrome do Cromossomo X Frágil
Limite:
Child
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Humans
Idioma:
En
Revista:
Am J Intellect Dev Disabil
Assunto da revista:
TRANSTORNOS MENTAIS
Ano de publicação:
2021
Tipo de documento:
Article