The Effects of pH and Excipients on Exenatide Stability in Solution.

Benet, Alexander; Halseth, Troy; Kang, Jukyung; Kim, April; Ackermann, Rose; Srinivasan, Santhanakrishnan; Schwendeman, Steven; Schwendeman, Anna

Benet, Alexander; Halseth, Troy; Kang, Jukyung; Kim, April; Ackermann, Rose; Srinivasan, Santhanakrishnan; Schwendeman, Steven; Schwendeman, Anna.

Afiliação

Benet A; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
Halseth T; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
Kang J; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
Kim A; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
Ackermann R; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
Srinivasan S; Xiromed, 180 Park Ave, Suite 101, Florham Park, NJ 07932, USA.
Schwendeman S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
Schwendeman A; Biointerfaces Institute, National Community Reinvestment Coalition, 2800 Plymouth Rd, Ann Arbor, MI 48109, USA.

Pharmaceutics ; 13(8)2021 Aug 16.

Article em En | MEDLINE | ID: mdl-34452224

Palavras-chave

GLP1 agonists; analytical characterization; diabetes; exenatide; generic peptides; physical/chemical degradation

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos