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Vaccine design and delivery approaches for COVID-19.
Shahzamani, Kiana; Mahmoudian, Fatemeh; Ahangarzadeh, Shahrzad; Ranjbar, Mohammad Mehdi; Beikmohammadi, Leila; Bahrami, Samira; Mohammadi, Elmira; Esfandyari, Sahar; Alibakhshi, Abbas; Javanmard, Shaghayegh Haghjooy.
Afiliação
  • Shahzamani K; Isfahan Gastroenterology and Hepatology Research Center (lGHRC), Isfahan University of Medical Sciences, Isfahan, Iran.
  • Mahmoudian F; Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Ahangarzadeh S; Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Ranjbar MM; Razi Vaccine and Serum Research Institute, Agricultural Research, Education, and Extension Organization (AREEO), Karaj, Iran.
  • Beikmohammadi L; Department of Biochemistry, Erasmus University Medical Center, Rotterdam, the Netherlands; Stem Cell and Regenerative Medicine Center of Excellence, Tehran University of Medical Sciences, 14155-6559 Tehran, Iran.
  • Bahrami S; Biotechnology Department, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
  • Mohammadi E; Applied Physiology Research Center, Cardiovascular Research Institute, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran; Core Research Facilities, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Esfandyari S; Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Alibakhshi A; Molecular Medicine Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: alibakhshi2630@yahoo.com.
  • Javanmard SH; Applied Physiology Research Center, Cardiovascular Research Institute, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: sh_haghjoo@med.mui.ac.ir.
Int Immunopharmacol ; 100: 108086, 2021 Nov.
Article em En | MEDLINE | ID: mdl-34454291
ABSTRACT
COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irã