Come one, come all? Re-evaluating RNA polymerase II pre-initiation complex assembly using single-molecule microscopy.

Hou, Tim Y; Kraus, W Lee

Hou, Tim Y; Kraus, W Lee.

Afiliação

Hou TY; Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Division of Basic Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Kraus WL; Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Division of Basic Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: lee.kraus@utsouthwestern.edu.

Mol Cell ; 81(17): 3443-3445, 2021 09 02.

Article em En | MEDLINE | ID: mdl-34478651

ABSTRACT

ABSTRACT

Complementary papers by Nguyen et al. (2021) and Baek et al. (2021) track the assembly of the pre-initiation complexes at gene promoters using single-molecule microscopy, revealing dynamic spatiotemporal regulation of transcription initiation.

Assuntos

RNA Polimerase II; Imagem Individual de Molécula; Regiões Promotoras Genéticas; RNA Polimerase II/genética; RNA Polimerase II/metabolismo

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: RNA Polimerase II / Imagem Individual de Molécula Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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