Predictive Value of Lymphocyte-to-monocyte Ratio in Patients with Contrast-induced Nephropathy After Percutaneous Coronary Intervention for Acute Coronary Syndrome.
J Transl Int Med
; 9(2): 123-130, 2021 Jun.
Article
em En
| MEDLINE
| ID: mdl-34497751
ABSTRACT
BACKGROUND AND OBJECTIVES:
Lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation, which is associated with adverse outcomes in cardiovascular diseases. The aim of this study was to evaluate whether admission LMR is associated with contrast-induced nephropathy (CIN) in patients who underwent percutaneous coronary intervention for acute coronary syndrome (ACS).METHODS:
A total of 873 patients were assessed. LMR was calculated via dividing lymphocyte count by monocyte count.RESULTS:
LMR was significantly lower in the with-CIN group. ROC analysis showed that the LMR ratios <2.52 predicted CIN development with sensitivity of 66.3% and specificity of 55.8%. Multivariate analysis showed that eGFR, admission glucose, and LMR were independent predictors of CIN in patients with ACS.CONCLUSION:
LMR is an easily accessible marker and could be used as a predictor of CIN in patients with ACS undergoing percutaneous coronary intervention.
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Bases de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Transl Int Med
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Turquia