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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.
Simeoni, Fabrizio; Romero-Camarero, Isabel; Camera, Francesco; Amaral, Fabio M R; Sinclair, Oliver J; Papachristou, Evangelia K; Spencer, Gary J; Lie-A-Ling, Michael; Lacaud, Georges; Wiseman, Daniel H; Carroll, Jason S; Somervaille, Tim C P.
Afiliação
  • Simeoni F; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK.
  • Romero-Camarero I; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK.
  • Camera F; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK.
  • Amaral FMR; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK.
  • Sinclair OJ; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK.
  • Papachristou EK; Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Spencer GJ; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK.
  • Lie-A-Ling M; Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Macclesfield SK10 4TG, UK.
  • Lacaud G; Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Macclesfield SK10 4TG, UK.
  • Wiseman DH; Epigenetics of Haematopoiesis Group, Oglesby Cancer Research Building, The University of Manchester, Manchester M20 4GJ, UK.
  • Carroll JS; Cancer Research UK Cambridge Institute, Cambridge CB2 0RE, UK.
  • Somervaille TCP; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4GJ, UK. Electronic address: tim.somervaille@cruk.manchester.ac.uk.
Cell Rep ; 36(12): 109725, 2021 09 21.
Article em En | MEDLINE | ID: mdl-34551306
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Diferenciação Celular / Fatores de Transcrição Forkhead / Subunidade alfa 2 de Fator de Ligação ao Core / Proteínas Correpressoras Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Diferenciação Celular / Fatores de Transcrição Forkhead / Subunidade alfa 2 de Fator de Ligação ao Core / Proteínas Correpressoras Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido