Supramolecular organization and biological interaction of squalenoyl siRNA nanoparticles.

Caillaud, Marie; Gobeaux, Frédéric; Hémadi, Miryana; Boutary, Suzan; Guenoun, Patrick; Desmaële, Didier; Couvreur, Patrick; Wien, Frank; Testard, Fabienne; Massaad-Massade, Liliane

Caillaud, Marie; Gobeaux, Frédéric; Hémadi, Miryana; Boutary, Suzan; Guenoun, Patrick; Desmaële, Didier; Couvreur, Patrick; Wien, Frank; Testard, Fabienne; Massaad-Massade, Liliane.

Afiliação

Caillaud M; U1195 Diseases and Hormones of the Nervous System, INSERM U1195 and University Paris-Saclay, 94276 Le Kremlin-Bicêtre, France.
Gobeaux F; Université Paris-Saclay, CEA, CNRS, NIMBE, LIONS, 91191 Gif-sur-Yvette, France.
Hémadi M; Université de Paris, CNRS-UMR 7086, Interfaces, Traitements, Organisation et DYnamique des Systèmes (ITODYS), UFR de Chimie, 75013 Paris, France.
Boutary S; U1195 Diseases and Hormones of the Nervous System, INSERM U1195 and University Paris-Saclay, 94276 Le Kremlin-Bicêtre, France.
Guenoun P; Université Paris-Saclay, CEA, CNRS, NIMBE, LIONS, 91191 Gif-sur-Yvette, France.
Desmaële D; Institut Galien Paris-Saclay, CNRS UMR 8612, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
Couvreur P; Institut Galien Paris-Saclay, CNRS UMR 8612, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
Wien F; SOLEIL Synchrotron, Saint Aubin, France.
Testard F; Université Paris-Saclay, CEA, CNRS, NIMBE, LIONS, 91191 Gif-sur-Yvette, France.
Massaad-Massade L; U1195 Diseases and Hormones of the Nervous System, INSERM U1195 and University Paris-Saclay, 94276 Le Kremlin-Bicêtre, France. Electronic address: liliane.massade@inserm.fr.

Int J Pharm ; 609: 121117, 2021 Nov 20.

Article em En | MEDLINE | ID: mdl-34562556

Assuntos

Nanopartículas; RNA Interferente Pequeno; Espalhamento a Baixo Ângulo; Esqualeno; Difração de Raios X

Palavras-chave

2-dioleoyl-sn-glycéro-3-phosphoethanolamine); 3dioleoyloxyN [2(sperminecarboxamido)ethyl]N; Azido-Squalene (N(3)-SQ); Biological interaction; Bovine serum albumin (BSA); Lipofectamine 3:1 DOSPA (2; Low density lipoprotein (LDL); N-(hexamethylenyl)-6-oxohexanamide spacer (C6); Nanotechnologies; Ndimethyl1propaniminium trifluoroacetate) : DOPE (1; Structural studies; Sybr Green C(32)H(37)N(4)S; cationic squalenaldehyde hydrazinoguanidinium acetate salt (SQ(+)); dibenzylcyclooctyne (DBCO); siRNA

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Nanopartículas Idioma: En Revista: Int J Pharm Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França

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