Radial Flow Perfusion Enables Real-Time Profiling of Cellular Metabolism at Low Oxygen Levels with Hyperpolarized <sup>13</sup>C NMR Spectroscopy.

Mancuso, Anthony; Pourfathi, Mehrdad; Kiefer, Ryan M; Noji, Michael C; Siddiqui, Sarmad; Profka, Enri; Weber, Charles N; Pantel, Austin; Kadlecek, Stephen J; Rizi, Rahim; Gade, Terence P F

Radial Flow Perfusion Enables Real-Time Profiling of Cellular Metabolism at Low Oxygen Levels with Hyperpolarized ¹³C NMR Spectroscopy.

Mancuso, Anthony; Pourfathi, Mehrdad; Kiefer, Ryan M; Noji, Michael C; Siddiqui, Sarmad; Profka, Enri; Weber, Charles N; Pantel, Austin; Kadlecek, Stephen J; Rizi, Rahim; Gade, Terence P F.

Afiliação

Mancuso A; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
Pourfathi M; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kiefer RM; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Noji MC; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Siddiqui S; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Profka E; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Weber CN; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Pantel A; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kadlecek SJ; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rizi R; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gade TPF; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Metabolites ; 11(9)2021 Aug 26.

Article em En | MEDLINE | ID: mdl-34564392

Palavras-chave

DNP; NMR spectroscopy; cell immobilization; hyperpolarized 13C; microcarriers; oxygen transport; perfusion; radial flow

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Metabolites Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos