Development and validation of an ultra-high performance liquid chromatography with tandem mass spectrometry method for the simultaneous quantification of direct oral anticoagulants in human plasma.

Zhang, Yu-Fei; Liu, Xiao-Qin; Wang, Yang; Xu, Xin; Zhong, Ming-Kang; Zhang, Pu; Ma, Chun-Lai

Zhang, Yu-Fei; Liu, Xiao-Qin; Wang, Yang; Xu, Xin; Zhong, Ming-Kang; Zhang, Pu; Ma, Chun-Lai.

Afiliação

Zhang YF; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai 200040, PR China. Electronic address: zhangyufei19@126.com.
Liu XQ; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai 200040, PR China. Electronic address: xiaoqinliu18@fudan.edu.cn.
Wang Y; Shanghai University of Sport, Shanghai 200438, PR China.
Xu X; Shanghai University of Sport, Shanghai 200438, PR China.
Zhong MK; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai 200040, PR China.
Zhang P; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai 200040, PR China. Electronic address: zhangpu@huashan.org.cn.
Ma CL; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai 200040, PR China. Electronic address: machunlai@huashan.org.cn.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1182: 122952, 2021 Oct 01.

Article em En | MEDLINE | ID: mdl-34598085

Assuntos

Anticoagulantes/sangue; Cromatografia Líquida de Alta Pressão/métodos; Espectrometria de Massas em Tandem/métodos; Monitoramento de Medicamentos; Humanos; Limite de Detecção; Modelos Lineares; Reprodutibilidade dos Testes

Palavras-chave

DOAC; Human plasma; Simultaneous determination; Therapeutic drug monitoring; UHPLC-MS/MS

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Anticoagulantes Tipo de estudo: Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2021 Tipo de documento: Article

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