Surgical palliation in poorly differentiated neuroendocrine carcinoma of the hypopharynx: Case report.
Cancer Rep (Hoboken)
; 5(8): e1558, 2022 08.
Article
em En
| MEDLINE
| ID: mdl-34609069
ABSTRACT
BACKGROUND:
Primary neuroendocrine carcinomas (NECs) are very rare entities accounting for 0.49% of all malignancies. Within the head and neck, the most common sites are the larynx and paranasal sinuses, while the hypopharynx is seldom described. CASE We present a patient with a poorly differentiated metastatic NEC of the hypopharynx treated palliatively with organ-preserving surgery and post-operative chemotherapy, and literature review for well-documented pure hypopharyngeal NECs. Our patient died of chest infection during chemotherapy, 4 months after surgery.CONCLUSION:
Chemotherapy remains the mainstay of treatment in the presence of metastases with 2-year overall survival of 15.7%. Due to the aggressive nature of poorly differentiated metastatic NECs, surgical management is seldom considered. We report and advocate the successful palliative role of organ-preserving, minimally invasive trans-oral LASER micro-surgery and neck dissection to control loco-regional head and neck disease, safe-guarding better quality of home life, despite limited life expectancy for this condition.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Carcinoma Neuroendócrino
/
Hipofaringe
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Cancer Rep (Hoboken)
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Reino Unido