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Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy.
Bachireddy, Pavan; Azizi, Elham; Burdziak, Cassandra; Nguyen, Vinhkhang N; Ennis, Christina S; Maurer, Katie; Park, Cameron Y; Choo, Zi-Ning; Li, Shuqiang; Gohil, Satyen H; Ruthen, Neil G; Ge, Zhongqi; Keskin, Derin B; Cieri, Nicoletta; Livak, Kenneth J; Kim, Haesook T; Neuberg, Donna S; Soiffer, Robert J; Ritz, Jerome; Alyea, Edwin P; Pe'er, Dana; Wu, Catherine J.
Afiliação
  • Bachireddy P; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Hematopoietic Biology & Malignancy, University of Texas MD Anderson Cancer Center, Houst
  • Azizi E; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Biomedical Engineering and Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA. Electronic address: ea2690@columbia.edu.
  • Burdziak C; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Nguyen VN; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Ennis CS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Maurer K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Park CY; Department of Biomedical Engineering and Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA.
  • Choo ZN; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Li S; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Gohil SH; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Ruthen NG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Ge Z; Department of Hematopoietic Biology & Malignancy, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Keskin DB; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Cieri N; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Livak KJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Kim HT; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Neuberg DS; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Soiffer RJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Ritz J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Alyea EP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Pe'er D; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Parker Institute of Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: peerd@mskcc.org.
  • Wu CJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address: cwu@partners.org.
Cell Rep ; 37(6): 109992, 2021 11 09.
Article em En | MEDLINE | ID: mdl-34758319

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ativação Linfocitária / Linfócitos T / Leucemia / Imunoterapia Adotiva / Transfusão de Linfócitos / Transplante de Células-Tronco / Recidiva Local de Neoplasia Tipo de estudo: Observational_studies Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ativação Linfocitária / Linfócitos T / Leucemia / Imunoterapia Adotiva / Transfusão de Linfócitos / Transplante de Células-Tronco / Recidiva Local de Neoplasia Tipo de estudo: Observational_studies Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article