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Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Kratochvil, Sven; Shen, Chen-Hsiang; Lin, Ying-Cing; Xu, Kai; Nair, Usha; Da Silva Pereira, Lais; Tripathi, Prabhanshu; Arnold, Johan; Chuang, Gwo-Yu; Melzi, Eleonora; Schön, Arne; Zhang, Baoshan; Dillon, Marlon; Bonilla, Brian; Flynn, Barbara J; Kirsch, Kathrin H; Kisalu, Neville K; Kiyuka, Patience K; Liu, Tracy; Ou, Li; Pancera, Marie; Rawi, Reda; Reveiz, Mateo; Seignon, Kareen; Wang, Lawrence T; Waring, Michael T; Warner, John; Yang, Yongping; Francica, Joseph R; Idris, Azza H; Seder, Robert A; Kwong, Peter D; Batista, Facundo D.
Afiliação
  • Kratochvil S; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Shen CH; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Lin YC; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Xu K; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Nair U; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Da Silva Pereira L; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Tripathi P; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Arnold J; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Chuang GY; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Melzi E; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Schön A; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Zhang B; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Dillon M; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Bonilla B; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Flynn BJ; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kirsch KH; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Kisalu NK; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kiyuka PK; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Liu T; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Ou L; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Pancera M; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA; Vaccine Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Rawi R; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Reveiz M; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Seignon K; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Wang LT; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Waring MT; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Warner J; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Yang Y; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Francica JR; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Idris AH; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Seder RA; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: rseder@nih.gov.
  • Kwong PD; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: pdkwong@nih.gov.
  • Batista FD; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Department of Immunology, Harvard Medical School, Boston, MA, USA; Department of Microbiology, Harvard Medical School, Boston, MA, USA. Electronic address: fbatist
Immunity ; 54(12): 2859-2876.e7, 2021 12 14.
Article em En | MEDLINE | ID: mdl-34788599

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Plasmodium falciparum / Proteínas de Protozoários / Subpopulações de Linfócitos B / Vacinas Antimaláricas / Vacinas de DNA / Malária / Epitopos Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Plasmodium falciparum / Proteínas de Protozoários / Subpopulações de Linfócitos B / Vacinas Antimaláricas / Vacinas de DNA / Malária / Epitopos Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos