From Molecule to Behavior: Hypocretin/orexin Revisited From a Sex-dependent Perspective.
Endocr Rev
; 43(4): 743-760, 2022 07 13.
Article
em En
| MEDLINE
| ID: mdl-34792130
ABSTRACT
The hypocretin/orexin (Hcrt/Orx) system in the perifornical lateral hypothalamus has been recognized as a critical node in a complex network of neuronal systems controlling both physiology and behavior in vertebrates. Our understanding of the Hcrt/Orx system and its array of functions and actions has grown exponentially in merely 2 decades. This review will examine the latest progress in discerning the roles played by the Hcrt/Orx system in regulating homeostatic functions and in executing instinctive and learned behaviors. Furthermore, the gaps that currently exist in our knowledge of sex-related differences in this field of study are discussed.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neuropeptídeos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Endocr Rev
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos