Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder.

Gutridge, Anna M; Chakraborty, Soumen; Varga, Balazs R; Rhoda, Elizabeth S; French, Alexander R; Blaine, Arryn T; Royer, Quinten H; Cui, Haoyue; Yuan, Jinling; Cassell, Robert J; Szabó, Márk; Majumdar, Susruta; van Rijn, Richard M

Gutridge, Anna M; Chakraborty, Soumen; Varga, Balazs R; Rhoda, Elizabeth S; French, Alexander R; Blaine, Arryn T; Royer, Quinten H; Cui, Haoyue; Yuan, Jinling; Cassell, Robert J; Szabó, Márk; Majumdar, Susruta; van Rijn, Richard M.

Afiliação

Gutridge AM; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Chakraborty S; Center for Clinical Pharmacology, University of Heath Sciences and Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, MO, United States.
Varga BR; Center for Clinical Pharmacology, University of Heath Sciences and Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, MO, United States.
Rhoda ES; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
French AR; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Blaine AT; Purdue Institute for Integrative Neuroscience, West Lafayette, IN, United States.
Royer QH; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Cui H; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Yuan J; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Cassell RJ; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Szabó M; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Majumdar S; Purdue Institute for Drug Discovery, West Lafayette, IN, United States.
van Rijn RM; XiMo Hungary Ltd, Budapest, Hungary.

Front Pharmacol ; 12: 764885, 2021.

Article em En | MEDLINE | ID: mdl-34803709

Palavras-chave

alcohol use disorder; biased signaling; delta opioid receptor; kratom; nociception; reward; seizures

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos