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XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair.
Adamowicz, Marek; Hailstone, Richard; Demin, Annie A; Komulainen, Emilia; Hanzlikova, Hana; Brazina, Jan; Gautam, Amit; Wells, Sophie E; Caldecott, Keith W.
Afiliação
  • Adamowicz M; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Hailstone R; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Demin AA; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Komulainen E; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Hanzlikova H; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Brazina J; Department of Genome Dynamics, Institute of Molecular Genetics of the Czech Academy of Science, Prague, Czech Republic.
  • Gautam A; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Wells SE; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Caldecott KW; Genome Damage and Stability Centre and Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Brighton, UK.
Nat Cell Biol ; 23(12): 1287-1298, 2021 12.
Article em En | MEDLINE | ID: mdl-34811483

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Transcrição Gênica / Reparo do DNA / Quebras de DNA de Cadeia Simples / Proteases Específicas de Ubiquitina / Poli(ADP-Ribose) Polimerase-1 / Proteína 1 Complementadora Cruzada de Reparo de Raio-X Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Transcrição Gênica / Reparo do DNA / Quebras de DNA de Cadeia Simples / Proteases Específicas de Ubiquitina / Poli(ADP-Ribose) Polimerase-1 / Proteína 1 Complementadora Cruzada de Reparo de Raio-X Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido