Natural Products for Pancreatic Cancer Treatment: From Traditional Medicine to Modern Drug Discovery.
Nutrients
; 13(11)2021 Oct 26.
Article
em En
| MEDLINE
| ID: mdl-34836055
ABSTRACT
Pancreatic cancer, the seventh most lethal cancer around the world, is considered complicated cancer due to poor prognosis and difficulty in treatment. Despite all the conventional treatments, including surgical therapy and chemotherapy, the mortality rate is still high. Therefore, the possibility of using natural products for pancreatic cancer is increasing. In this study, 68 natural products that have anti-pancreatic cancer effects reported within five years were reviewed. The mechanisms of anti-cancer effects were divided into four types apoptosis, anti-metastasis, anti-angiogenesis, and anti-resistance. Most of the studies were conducted for natural products that induce apoptosis in pancreatic cancer. Among them, plant extracts such as Eucalyptus microcorys account for the major portion. Some natural products, including Moringa, Coix seed, etc., showed multi-functional properties. Natural products could be beneficial candidates for treating pancreatic cancer.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
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Produtos Biológicos
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Descoberta de Drogas
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Fitoterapia
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Medicina Tradicional
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Nutrients
Ano de publicação:
2021
Tipo de documento:
Article