Effect of topical application of platelet-rich plasma on chronic venous leg ulcerations.
Dermatol Ther
; 35(2): e15236, 2022 02.
Article
em En
| MEDLINE
| ID: mdl-34845807
ABSTRACT
Wound products that reliably support healing of chronic leg ulcers remain a huge unmet need in clinical practice. Due to the lack of standardized comparable protocols and different systems for platelet-rich plasma (PRP) preparation, there is limited data on healing rates in chronic venous ulcers. In our case series with a total of seven chronic leg ulcers in four patients, we investigated the healing rates based on standardized digital photographs of chronic venous ulcers after application of topical PRP using a digital imaging software. In 5 out of 7 ulcers, the PRP-treated wound half showed faster healing as compared the control half of the wound. In this case series, PRP-treated sides of chronic venous leg ulcers showed a tendency for accelerated healing as compared to nontreated collateral wound side. Our data support the evaluation of topical PRP treatment in the management of chronic venous leg ulcers.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Úlcera Varicosa
/
Plasma Rico em Plaquetas
/
Úlcera da Perna
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Dermatol Ther
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Suíça