New Horizons: Next-Generation Insulin Analogues: Structural Principles and Clinical Goals.

Jarosinski, Mark A; Chen, Yen-Shan; Varas, Nicolás; Dhayalan, Balamurugan; Chatterjee, Deepak; Weiss, Michael A

Jarosinski, Mark A; Chen, Yen-Shan; Varas, Nicolás; Dhayalan, Balamurugan; Chatterjee, Deepak; Weiss, Michael A.

Afiliação

Jarosinski MA; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Chen YS; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Varas N; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Dhayalan B; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Chatterjee D; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Weiss MA; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

J Clin Endocrinol Metab ; 107(4): 909-928, 2022 03 24.

Article em En | MEDLINE | ID: mdl-34850005

Assuntos

Diabetes Mellitus Tipo 2; Insulinas; Animais; Glicemia; Diabetes Mellitus Tipo 2/tratamento farmacológico; Objetivos; Humanos; Hipoglicemiantes/farmacocinética; Hipoglicemiantes/uso terapêutico; Insulina/farmacologia; Insulina/uso terapêutico; Insulinas/uso terapêutico

Palavras-chave

insulin action; insulin signaling; molecular pharmacology; protein design; protein engineering

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Insulinas Limite: Animals / Humans Idioma: En Revista: J Clin Endocrinol Metab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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