Mass spectrometry-based lipid analysis and imaging.
Curr Top Membr
; 88: 315-357, 2021.
Article
em En
| MEDLINE
| ID: mdl-34862030
ABSTRACT
Mass spectrometry imaging (MSI) is a powerful tool for in situ mapping of analytes across a sample. With growing interest in lipid biochemistry, the ability to perform such mapping without antibodies has opened many opportunities for MSI and lipid analysis. Herein, we discuss the basics of MSI with particular emphasis on MALDI mass spectrometry and lipid analysis. A discussion of critical advancements as well as protocol details are provided to the reader. In addition, strategies for improving the detection of lipids, as well as applications in biomedical research, are presented.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Lipídeos
Idioma:
En
Revista:
Curr Top Membr
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos