Korean Red Ginseng Improves Astrocytic Mitochondrial Function by Upregulating HO-1-Mediated AMPK&#945;-PGC-1&#945;-ERR&#945; Circuit after Traumatic Brain Injury.

Kim, Minsu; Kim, Joohwan; Moon, Sunhong; Choi, Bo Young; Kim, Sueun; Jeon, Hui Su; Suh, Sang Won; Kim, Young-Myeong; Choi, Yoon Kyung

Korean Red Ginseng Improves Astrocytic Mitochondrial Function by Upregulating HO-1-Mediated AMPKα-PGC-1α-ERRα Circuit after Traumatic Brain Injury.

Kim, Minsu; Kim, Joohwan; Moon, Sunhong; Choi, Bo Young; Kim, Sueun; Jeon, Hui Su; Suh, Sang Won; Kim, Young-Myeong; Choi, Yoon Kyung.

Afiliação

Kim M; Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Kim J; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon-do, Korea.
Moon S; Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Choi BY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Gangwon-do, Korea.
Kim S; Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Jeon HS; Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Suh SW; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Gangwon-do, Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon-do, Korea.
Choi YK; Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.

Int J Mol Sci ; 22(23)2021 Dec 03.

Article em En | MEDLINE | ID: mdl-34884886

Assuntos

Astrócitos/efeitos dos fármacos; Lesões Encefálicas Traumáticas/tratamento farmacológico; Heme Oxigenase-1/metabolismo; Mitocôndrias/metabolismo; Panax; Proteínas Quinases Ativadas por AMP/genética; Animais; Astrócitos/metabolismo; Astrócitos/fisiologia; Lesões Encefálicas Traumáticas/metabolismo; Lesões Encefálicas Traumáticas/fisiopatologia; Citocromos c/metabolismo; Regulação da Expressão Gênica; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Mitocôndrias/fisiologia; Biogênese de Organelas; Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo/genética; Receptores de Estrogênio/genética; Receptor ERRalfa Relacionado ao Estrogênio

Palavras-chave

AMPKαPGC-1αERRα circuit; Korean red ginseng; astrocytic mitochondrial function; heme oxygenase-1; traumatic brain injury

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Astrócitos / Heme Oxigenase-1 / Lesões Encefálicas Traumáticas / Panax / Mitocôndrias Limite: Animals / Humans / Male Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article

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