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Early lysosome defects precede neurodegeneration with amyloid-ß and tau aggregation in NHE6-null rat brain.
Lee, YouJin; Miller, Morgan R; Fernandez, Marty A; Berg, Elizabeth L; Prada, Adriana M; Ouyang, Qing; Schmidt, Michael; Silverman, Jill L; Young-Pearse, Tracy L; Morrow, Eric M.
Afiliação
  • Lee Y; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA.
  • Miller MR; Center for Translational Neuroscience, Carney Institute for Brain Science and Brown Institute for Translational Science (BITS), Brown University, Providence, RI 02912, USA.
  • Fernandez MA; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA.
  • Berg EL; Center for Translational Neuroscience, Carney Institute for Brain Science and Brown Institute for Translational Science (BITS), Brown University, Providence, RI 02912, USA.
  • Prada AM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Ouyang Q; MIND Institute and Department of Psychiatry and Behavioural Sciences, University of California Davis School of Medicine, Sacramento, CA, USA.
  • Schmidt M; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA.
  • Silverman JL; Center for Translational Neuroscience, Carney Institute for Brain Science and Brown Institute for Translational Science (BITS), Brown University, Providence, RI 02912, USA.
  • Young-Pearse TL; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA.
  • Morrow EM; Center for Translational Neuroscience, Carney Institute for Brain Science and Brown Institute for Translational Science (BITS), Brown University, Providence, RI 02912, USA.
Brain ; 145(9): 3187-3202, 2022 09 14.
Article em En | MEDLINE | ID: mdl-34928329

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença de Alzheimer / Microcefalia Limite: Animals Idioma: En Revista: Brain Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença de Alzheimer / Microcefalia Limite: Animals Idioma: En Revista: Brain Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos