Comparing nitisinone 2 mg and 10 mg in the treatment of alkaptonuria-An approach using statistical modelling.

Ranganath, Lakshminarayan R; Milan, Anna M; Hughes, Andrew T; Khedr, Milad; Norman, Brendan P; Alsbou, Mohammed; Imrich, Richard; Gornall, Matthew; Sireau, Nicolas; Gallagher, James A; Jackson, Richard

Ranganath, Lakshminarayan R; Milan, Anna M; Hughes, Andrew T; Khedr, Milad; Norman, Brendan P; Alsbou, Mohammed; Imrich, Richard; Gornall, Matthew; Sireau, Nicolas; Gallagher, James A; Jackson, Richard.

Afiliação

Ranganath LR; Departments of Clinical Biochemistry and Metabolic Medicine Liverpool University Hospitals NHS Foundation Trusts Liverpool UK.
Milan AM; Musculoskeletal Biology and Ageing University of Liverpool, William Henry Duncan Building Liverpool UK.
Hughes AT; Departments of Clinical Biochemistry and Metabolic Medicine Liverpool University Hospitals NHS Foundation Trusts Liverpool UK.
Khedr M; Musculoskeletal Biology and Ageing University of Liverpool, William Henry Duncan Building Liverpool UK.
Norman BP; Departments of Clinical Biochemistry and Metabolic Medicine Liverpool University Hospitals NHS Foundation Trusts Liverpool UK.
Alsbou M; Musculoskeletal Biology and Ageing University of Liverpool, William Henry Duncan Building Liverpool UK.
Imrich R; Departments of Clinical Biochemistry and Metabolic Medicine Liverpool University Hospitals NHS Foundation Trusts Liverpool UK.
Gornall M; Musculoskeletal Biology and Ageing University of Liverpool, William Henry Duncan Building Liverpool UK.
Sireau N; Faculty of Medicine Mutah University Karak Jordan.
Gallagher JA; National Institute of Rheumatic Diseases Piestany Slovakia.
Jackson R; Biomedical Research Center, Slovak Academy of Sciences Bratislava Slovakia.

JIMD Rep ; 63(1): 80-92, 2022 Jan.

Article em En | MEDLINE | ID: mdl-35028273

Palavras-chave

AKUSSI; alkaptonuria; disease progression; homogentisic acid; nitisinone; safety; slope analysis

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Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: JIMD Rep Ano de publicação: 2022 Tipo de documento: Article