Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury.

Cox, Christopher R; Lynch, Stephen; Goldring, Christopher; Sharma, Parveen

Cox, Christopher R; Lynch, Stephen; Goldring, Christopher; Sharma, Parveen.

Afiliação

Cox CR; Department of Pharmacology and Experimental Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Lynch S; Department of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.
Goldring C; Department of Pharmacology and Experimental Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Sharma P; Department of Pharmacology and Experimental Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.

Front Med Technol ; 2: 611913, 2020.

Article em En | MEDLINE | ID: mdl-35047893

Palavras-chave

3D; DILI; HLC; hepatocyte; in-vitro; liver; metabolism; spheroids

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Front Med Technol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido