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Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.
Kandasamy, Pachamuthu; McClorey, Graham; Shimizu, Mamoru; Kothari, Nayantara; Alam, Rowshon; Iwamoto, Naoki; Kumarasamy, Jayakanthan; Bommineni, Gopal R; Bezigian, Adam; Chivatakarn, Onanong; Butler, David C D; Byrne, Michael; Chwalenia, Katarzyna; Davies, Kay E; Desai, Jigar; Shelke, Juili Dilip; Durbin, Ann F; Ellerington, Ruth; Edwards, Ben; Godfrey, Jack; Hoss, Andrew; Liu, Fangjun; Longo, Kenneth; Lu, Genliang; Marappan, Subramanian; Oieni, Jacopo; Paik, Ik-Hyeon; Estabrook, Erin Purcell; Shivalila, Chikdu; Tischbein, Maeve; Kawamoto, Tomomi; Rinaldi, Carlo; Rajão-Saraiva, Joana; Tripathi, Snehlata; Yang, Hailin; Yin, Yuan; Zhao, Xiansi; Zhou, Cong; Zhang, Jason; Apponi, Luciano; Wood, Matthew J A; Vargeese, Chandra.
Afiliação
  • Kandasamy P; Wave Life Sciences, Cambridge, MA, USA.
  • McClorey G; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.
  • Shimizu M; Wave Life Sciences, Cambridge, MA, USA.
  • Kothari N; Wave Life Sciences, Cambridge, MA, USA.
  • Alam R; Wave Life Sciences, Cambridge, MA, USA.
  • Iwamoto N; Wave Life Sciences, Cambridge, MA, USA.
  • Kumarasamy J; Wave Life Sciences, Cambridge, MA, USA.
  • Bommineni GR; Wave Life Sciences, Cambridge, MA, USA.
  • Bezigian A; Wave Life Sciences, Cambridge, MA, USA.
  • Chivatakarn O; Wave Life Sciences, Cambridge, MA, USA.
  • Butler DCD; Wave Life Sciences, Cambridge, MA, USA.
  • Byrne M; Wave Life Sciences, Cambridge, MA, USA.
  • Chwalenia K; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.
  • Davies KE; Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK.
  • Desai J; Wave Life Sciences, Cambridge, MA, USA.
  • Shelke JD; Wave Life Sciences, Cambridge, MA, USA.
  • Durbin AF; Wave Life Sciences, Cambridge, MA, USA.
  • Ellerington R; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.
  • Edwards B; Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK.
  • Godfrey J; Wave Life Sciences, Cambridge, MA, USA.
  • Hoss A; Wave Life Sciences, Cambridge, MA, USA.
  • Liu F; Wave Life Sciences, Cambridge, MA, USA.
  • Longo K; Wave Life Sciences, Cambridge, MA, USA.
  • Lu G; MDUK Oxford Neuromuscular Centre, University of Oxford, Oxford OX2 9DU, UK.
  • Marappan S; Wave Life Sciences, Cambridge, MA, USA.
  • Oieni J; Wave Life Sciences, Cambridge, MA, USA.
  • Paik IH; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.
  • Estabrook EP; Wave Life Sciences, Cambridge, MA, USA.
  • Shivalila C; Wave Life Sciences, Cambridge, MA, USA.
  • Tischbein M; Wave Life Sciences, Cambridge, MA, USA.
  • Kawamoto T; Wave Life Sciences, Cambridge, MA, USA.
  • Rinaldi C; Wave Life Sciences, Cambridge, MA, USA.
  • Rajão-Saraiva J; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.
  • Tripathi S; MDUK Oxford Neuromuscular Centre, University of Oxford, Oxford OX2 9DU, UK.
  • Yang H; Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK.
  • Yin Y; Wave Life Sciences, Cambridge, MA, USA.
  • Zhao X; Wave Life Sciences, Cambridge, MA, USA.
  • Zhou C; Wave Life Sciences, Cambridge, MA, USA.
  • Zhang J; Wave Life Sciences, Cambridge, MA, USA.
  • Apponi L; Wave Life Sciences, Cambridge, MA, USA.
  • Wood MJA; Wave Life Sciences, Cambridge, MA, USA.
  • Vargeese C; Wave Life Sciences, Cambridge, MA, USA.
Nucleic Acids Res ; 50(10): 5443-5466, 2022 06 10.
Article em En | MEDLINE | ID: mdl-35061895
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Distrofia Muscular de Duchenne / Oligonucleotídeos Fosforotioatos Limite: Animals Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Distrofia Muscular de Duchenne / Oligonucleotídeos Fosforotioatos Limite: Animals Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos