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Dose-dependent bioavailability and tissue distribution of the ATR inhibitor AZD6738 (ceralasertib) in mice.
Kiesel, Brian F; Guo, Jianxia; Parise, Robert A; Venkataramanan, Raman; Clump, David A; Bakkenist, Christopher J; Beumer, Jan H.
Afiliação
  • Kiesel BF; Cancer Therapeutics Drug Discovery Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
  • Guo J; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.
  • Parise RA; Cancer Therapeutics Drug Discovery Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
  • Venkataramanan R; Cancer Therapeutics Drug Discovery Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
  • Clump DA; Cancer Therapeutics Drug Discovery Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
  • Bakkenist CJ; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Beumer JH; Department of Radiation Oncology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Cancer Chemother Pharmacol ; 89(2): 231-242, 2022 02.
Article em En | MEDLINE | ID: mdl-35066692
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Morfolinas / Inibidores de Proteínas Quinases / Indóis / Modelos Biológicos Limite: Animals Idioma: En Revista: Cancer Chemother Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Morfolinas / Inibidores de Proteínas Quinases / Indóis / Modelos Biológicos Limite: Animals Idioma: En Revista: Cancer Chemother Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos