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Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
Johnson, Erik C B; Carter, E Kathleen; Dammer, Eric B; Duong, Duc M; Gerasimov, Ekaterina S; Liu, Yue; Liu, Jiaqi; Betarbet, Ranjita; Ping, Lingyan; Yin, Luming; Serrano, Geidy E; Beach, Thomas G; Peng, Junmin; De Jager, Philip L; Haroutunian, Vahram; Zhang, Bin; Gaiteri, Chris; Bennett, David A; Gearing, Marla; Wingo, Thomas S; Wingo, Aliza P; Lah, James J; Levey, Allan I; Seyfried, Nicholas T.
Afiliação
  • Johnson ECB; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA. erik.c.b.johnson@emory.edu.
  • Carter EK; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA. erik.c.b.johnson@emory.edu.
  • Dammer EB; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Duong DM; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • Gerasimov ES; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Liu Y; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
  • Liu J; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Betarbet R; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
  • Ping L; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • Yin L; Department of Genetics, Emory University School of Medicine, Atlanta, GA, USA.
  • Serrano GE; Department of Genetics, Emory University School of Medicine, Atlanta, GA, USA.
  • Beach TG; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Peng J; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • De Jager PL; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Haroutunian V; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • Zhang B; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
  • Gaiteri C; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
  • Bennett DA; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Gearing M; Banner Sun Health Research Institute, Sun City, AZ, USA.
  • Wingo TS; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Wingo AP; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Lah JJ; Center for Translational & Computational Neuroimmunology, Department of Neurology, Taub Institute, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY, USA.
  • Levey AI; Departments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Seyfried NT; James J. Peters VA Medical Center MIRECC, Bronx, NY, USA.
Nat Neurosci ; 25(2): 213-225, 2022 02.
Article em En | MEDLINE | ID: mdl-35115731
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Limite: Humans Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Limite: Humans Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos