Revealing Clonal Responses of Tumor-Reactive T-Cells Through T Cell Receptor Repertoire Analysis.

Aoki, Hiroyasu; Shichino, Shigeyuki; Matsushima, Kouji; Ueha, Satoshi

Aoki, Hiroyasu; Shichino, Shigeyuki; Matsushima, Kouji; Ueha, Satoshi.

Afiliação

Aoki H; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
Shichino S; Department of Hygiene, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Matsushima K; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
Ueha S; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.

Front Immunol ; 13: 807696, 2022.

Article em En | MEDLINE | ID: mdl-35154125

Assuntos

Neoplasias/imunologia; Receptores de Antígenos de Linfócitos T/genética; Receptores de Antígenos de Linfócitos T/imunologia; Microambiente Tumoral/imunologia; Animais; Linfócitos T CD8-Positivos/imunologia; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Ativação Linfocitária/imunologia; Camundongos; Receptores de Antígenos de Linfócitos T/classificação

Palavras-chave

CD8+ T cell; T-cell receptor repertoire; cancer-immunity cycle; immune check inhibitors; inter-organ clone tracking; single-cell TCR-seq

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Microambiente Tumoral / Neoplasias Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão

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