Administration of an Acidic Sphingomyelinase (ASMase) Inhibitor, Imipramine, Reduces Hypoglycemia-Induced Hippocampal Neuronal Death.

Kho, A Ra; Choi, Bo Young; Lee, Song Hee; Hong, Dae Ki; Kang, Beom Seok; Lee, Si Hyun; Suh, Sang Won

Kho, A Ra; Choi, Bo Young; Lee, Song Hee; Hong, Dae Ki; Kang, Beom Seok; Lee, Si Hyun; Suh, Sang Won.

Afiliação

Kho AR; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.
Choi BY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.
Lee SH; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.
Hong DK; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.
Kang BS; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.
Lee SH; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.
Suh SW; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Kangwon-do, Korea.

Cells ; 11(4)2022 02 14.

Article em En | MEDLINE | ID: mdl-35203316

Assuntos

Hipoglicemia; Imipramina; Ceramidas/metabolismo; Hipocampo/metabolismo; Humanos; Hipoglicemia/tratamento farmacológico; Imipramina/farmacologia; Esfingomielina Fosfodiesterase/antagonistas & inibidores

Palavras-chave

acidic sphingomyelinase; ceramide; cognitive dysfunction; hypoglycemia; imipramine; neuron death; sphingolipid

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Hipoglicemia / Imipramina Limite: Humans Idioma: En Revista: Cells Ano de publicação: 2022 Tipo de documento: Article

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