The Role of <i>SMAD4</i> Inactivation in Epithelial-Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?

Racu, Marie-Lucie; Lebrun, Laetitia; Schiavo, Andrea Alex; Van Campenhout, Claude; De Clercq, Sarah; Absil, Lara; Minguijon Perez, Esmeralda; Maris, Calliope; Decaestecker, Christine; Salmon, Isabelle; D'Haene, Nicky

The Role of SMAD4 Inactivation in Epithelial-Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?

Racu, Marie-Lucie; Lebrun, Laetitia; Schiavo, Andrea Alex; Van Campenhout, Claude; De Clercq, Sarah; Absil, Lara; Minguijon Perez, Esmeralda; Maris, Calliope; Decaestecker, Christine; Salmon, Isabelle; D'Haene, Nicky.

Afiliação

Racu ML; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Lebrun L; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Schiavo AA; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Van Campenhout C; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
De Clercq S; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Absil L; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Minguijon Perez E; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Maris C; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Decaestecker C; DIAPath, Center for Microscopy and Molecular Imaging (CMMI), Université Libre de Bruxelles (ULB), 6041 Gosselies, Belgium.
Salmon I; Laboratory of Image Synthesis and Analysis, Brussels School of Engineering/École Polytechnique de Brussels, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium.
D'Haene N; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.

Cancers (Basel) ; 14(4)2022 Feb 15.

Article em En | MEDLINE | ID: mdl-35205719

Palavras-chave

EMT; PDAC; SMAD4; biomarker; epithelialmesenchymal plasticity; epithelialmesenchymal transition; metastasis; pancreatic ductal adenocarcinoma

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Bélgica