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Human IL-2Rɑ subunit binding modulation of IL-2 through a decline in electrostatic interactions: A computational and experimental approach.
Beig Parikhani, Arezoo; Bagherzadeh, Kowsar; Dehghan, Rada; Biglari, Alireza; Shokrgozar, Mohammad Ali; Riazi Rad, Farhad; Zeinali, Sirous; Talebkhan, Yeganeh; Ajdary, Soheila; Ahangari Cohan, Reza; Behdani, Mahdi.
Afiliação
  • Beig Parikhani A; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
  • Bagherzadeh K; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran.
  • Dehghan R; Stem Cell and Regenerative Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Biglari A; Eye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
  • Shokrgozar MA; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
  • Riazi Rad F; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran.
  • Zeinali S; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Talebkhan Y; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
  • Ajdary S; Department of Immunology, Pasteur Institute of Iran, Tehran, Iran.
  • Ahangari Cohan R; Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
  • Behdani M; Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
PLoS One ; 17(2): e0264353, 2022.
Article em En | MEDLINE | ID: mdl-35213635

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Subunidade alfa de Receptor de Interleucina-2 / Eletricidade Estática / Simulação de Dinâmica Molecular / Simulação de Acoplamento Molecular Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Subunidade alfa de Receptor de Interleucina-2 / Eletricidade Estática / Simulação de Dinâmica Molecular / Simulação de Acoplamento Molecular Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irã