Development and validation of an UHPLC-Orbitrap-HRMS method for rapid determination of endogenous L-carnitine in patients on hemodialysis/peritoneal dialysis and its application to promote rational drug use.

Jiang, Wen-Ting; Tang, Liu-Xing; Pan, Jie; Su, Cun-Jin; Shen, Zhu; Hu, Zhan-Hong; Zhan, Zhou-Bing; Shi, Ai-Ming

Jiang, Wen-Ting; Tang, Liu-Xing; Pan, Jie; Su, Cun-Jin; Shen, Zhu; Hu, Zhan-Hong; Zhan, Zhou-Bing; Shi, Ai-Ming.

Afiliação

Jiang WT; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Tang LX; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Pan J; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Su CJ; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Shen Z; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Hu ZH; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Zhan ZB; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Shi AM; Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Ann Transl Med ; 10(2): 103, 2022 Jan.

Article em En | MEDLINE | ID: mdl-35282068

Palavras-chave

L-carnitine; UHPLC-Orbitrap-HRMS; dialysis; fortified validation; rational drug use

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Ann Transl Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China