Vildagliptin improves neurological function by inhibiting apoptosis and ferroptosis following intracerebral hemorrhage in mice.

Zhang, Yan; Zhang, Xiangyu; Wee Yong, V; Xue, Mengzhou

Zhang, Yan; Zhang, Xiangyu; Wee Yong, V; Xue, Mengzhou.

Afiliação

Zhang Y; Departments of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.
Zhang X; Departments of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.
Wee Yong V; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada. Electronic address: vyong@ucalgary.ca.
Xue M; Departments of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China. Electronic address: xuemengzhou@zzu.edu.cn.

Neurosci Lett ; 776: 136579, 2022 04 17.

Article em En | MEDLINE | ID: mdl-35304193

Assuntos

Ferroptose; Fármacos Neuroprotetores; Animais; Apoptose; Hemorragia Cerebral/metabolismo; Camundongos; Fármacos Neuroprotetores/farmacologia; Fármacos Neuroprotetores/uso terapêutico; Vildagliptina/farmacologia; Vildagliptina/uso terapêutico

Palavras-chave

Apoptosis; Dipeptidyl peptidase-4 inhibitor; Ferroptosis; Intracerebral hemorrhage; Neuroinflammation; Vildagliptin

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Ferroptose Limite: Animals Idioma: En Revista: Neurosci Lett Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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