Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination.

Eisenmann, Eric D; Garrison, Dominique A; Talebi, Zahra; Jin, Yan; Silvaroli, Josie A; Kim, Jin-Gyu; Sparreboom, Alex; Savona, Michael R; Mims, Alice S; Baker, Sharyn D

Eisenmann, Eric D; Garrison, Dominique A; Talebi, Zahra; Jin, Yan; Silvaroli, Josie A; Kim, Jin-Gyu; Sparreboom, Alex; Savona, Michael R; Mims, Alice S; Baker, Sharyn D.

Afiliação

Eisenmann ED; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Garrison DA; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Talebi Z; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Jin Y; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Silvaroli JA; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Kim JG; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Sparreboom A; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Savona MR; Vanderbilt-Ingram Cancer Center, Division of Hematology and Oncology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Mims AS; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Baker SD; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

Pharmaceutics ; 14(4)2022 Mar 23.

Article em En | MEDLINE | ID: mdl-35456528

Palavras-chave

CYP3A; OATP1B1; antifungal; pharmacokinetics; venetoclax

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos