Two new iridoid glycosides from <i>Hedyotis diffusa</i>.

Wu, Juan; Ye, Zhu-Jun; Yu, Li-Juan; Chen, Xuan-Qin

Two new iridoid glycosides from Hedyotis diffusa.

Wu, Juan; Ye, Zhu-Jun; Yu, Li-Juan; Chen, Xuan-Qin.

Afiliação

Wu J; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Ye ZJ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Yu LJ; Agro-Products Processing Research Institute, Yunnan Academy of Agricultural Sciences, Kunming 650221, China.
Chen XQ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.

J Asian Nat Prod Res ; 25(1): 27-35, 2023 Jan.

Article em En | MEDLINE | ID: mdl-35503565

ABSTRACT

ABSTRACT

Two new iridoid glycosides, named productasperulosidic acid butyl ester (1) and E-6-O-3-hydroxy-p-methoxycinnamoyl scandoside methyl ester (2), along with nine known ones (3-11), were isolated from Hedyotis diffusa Willd. The structures of them were elucidated by extensive 1D, 2D NMR and HR-ESI-MS spectral data. Compounds 1-11 showed no significant cytotoxic activity against HeLa cells.

Assuntos

Medicamentos de Ervas Chinesas; Hedyotis; Humanos; Glicosídeos Iridoides; Hedyotis/química; Células HeLa; Estrutura Molecular; Medicamentos de Ervas Chinesas/farmacologia; Medicamentos de Ervas Chinesas/química

Palavras-chave

E-6-O-3-hydroxy-p-methoxycinnamoyl scandoside methyl ester; Hedyotis diffusa; Rubiaceae; asperulosidic acid butyl ester; cytotoxic activity; iridoid glycoside

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Hedyotis Limite: Humans Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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