c-MYC-mediated TRIB3/P62<sup>+</sup> aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2.

Su, Min-Xia; Xu, Yu-Lian; Jiang, Xiao-Ming; Huang, Mu-Yang; Zhang, Le-Le; Yuan, Luo-Wei; Xu, Xiao-Huang; Zhu, Qi; Gao, Jian-Li; Lu, Jia-Hong; Chen, Xiuping; Huang, Ming-Qing; Wang, Yitao; Lu, Jin-Jian

c-MYC-mediated TRIB3/P62⁺ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2.

Su, Min-Xia; Xu, Yu-Lian; Jiang, Xiao-Ming; Huang, Mu-Yang; Zhang, Le-Le; Yuan, Luo-Wei; Xu, Xiao-Huang; Zhu, Qi; Gao, Jian-Li; Lu, Jia-Hong; Chen, Xiuping; Huang, Ming-Qing; Wang, Yitao; Lu, Jin-Jian.

Afiliação

Su MX; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Xu YL; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Jiang XM; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Huang MY; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Zhang LL; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Yuan LW; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Xu XH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Zhu Q; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Gao JL; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310000, China.
Lu JH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Chen X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Huang MQ; College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350000, China.
Wang Y; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Lu JJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.

Acta Pharm Sin B ; 12(3): 1240-1253, 2022 Mar.

Article em En | MEDLINE | ID: mdl-35530150

Palavras-chave

Aggresomes; Everolimus; Ginsenoside Rh2; Lung cancer; P62; Paraptosis; TRIB3; c-MYC

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Acta Pharm Sin B Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China