Abiraterone Acetate Attenuates SARS-CoV-2 Replication by Interfering with the Structural Nucleocapsid Protein.

Kim, Jinsoo; Hwang, Seok Young; Kim, Dongbum; Kim, Minyoung; Baek, Kyeongbin; Kang, Mijeong; An, Seungchan; Gong, Junpyo; Park, Sangkyu; Kandeel, Mahmoud; Lee, Younghee; Noh, Minsoo; Kwon, Hyung-Joo

Kim, Jinsoo; Hwang, Seok Young; Kim, Dongbum; Kim, Minyoung; Baek, Kyeongbin; Kang, Mijeong; An, Seungchan; Gong, Junpyo; Park, Sangkyu; Kandeel, Mahmoud; Lee, Younghee; Noh, Minsoo; Kwon, Hyung-Joo.

Afiliação

Kim J; Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.
Hwang SY; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Kim D; Institute of Medical Science, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.
Kim M; Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.
Baek K; Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.
Kang M; Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.
An S; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Gong J; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Park S; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju 28644, Republic of Korea.
Kandeel M; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-hofuf 31982, Saudi Arabia.
Lee Y; Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelshikh University, Kafrelshikh 33516, Egypt.
Noh M; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju 28644, Republic of Korea.
Kwon HJ; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.

Biomol Ther (Seoul) ; 30(5): 427-434, 2022 Sep 01.

Article em En | MEDLINE | ID: mdl-35548881

Palavras-chave

Abiraterone acetate; Docking simulation; Drug repurposing; Nucleocapsid protein; SARS-CoV-2; Virtual screening

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Biomol Ther (Seoul) Ano de publicação: 2022 Tipo de documento: Article