Enhanced osteoarthritis therapy by nanoengineered mesenchymal stem cells using biomimetic CuS nanoparticles loaded with plasmid DNA encoding TGF-ß1.

Cai, Yu; Wu, Cuixi; Ou, Qianhua; Zeng, Muhui; Xue, Song; Chen, Jieli; Lu, Yao; Ding, Changhai

Cai, Yu; Wu, Cuixi; Ou, Qianhua; Zeng, Muhui; Xue, Song; Chen, Jieli; Lu, Yao; Ding, Changhai.

Afiliação

Cai Y; Clinical Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Wu C; Orthopedic Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Ou Q; Clinical Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Zeng M; Clinical Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Xue S; Clinical Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Chen J; Orthopedic Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Lu Y; Clinical Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Ding C; Department of Rheumatology and Immunology, Arthritis Research Institute, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230032, China.

Bioact Mater ; 19: 444-457, 2023 Jan.

Article em En | MEDLINE | ID: mdl-35574050

Palavras-chave

Cartilage regeneration; Cupper sulfide nanoparticles; Gene delivery; Osteoarthritis; Stem cell therapy

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Bioact Mater Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China